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EORTC AISBL / IVZW |
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EORTC AISBL / IVZW |
Open studies are marked with a purple background, closed studies have a grey background, studies to be opened have a white background
| 26021 | Observation versus conventional-fractionated radiotherapy or radiosurgery after non-radical surgery for benign intracranial meningiomas : a phase III study |
| 11011 | Early phase II study on BNCT in metastatic malignant melanoma using the boron carrier BPA |
| 22994 | A Phase I Study on the Feasibility of High Dose Three-Dimensional Conformal Radiotherapy in Patients with Inoperable and Locally Advanced Non Small Cell Lung Cancer. |
| 24001 | Randomized phase III study on the selection of the target volume in postoperative radiotherapy for cervical lymph node metastases of squamous cell carcinoma from an unknown primary (CUP) |
| 40001 | Randomized study of pre-operative radio-chemotherapy versus surgery alone in thoracic oesophageal cancer deemed to be resectable |
| 05991 | A phase II study of chronomodulated preoperative infusional chemoradiation for biliary tract cancer |
| 10974 | LAMANOMA: Conservative local treatment versus mastectomy after induction chemotherapy in locally advanced breast cancer: a randomized phase III study. |
| 08981 | Surgical treatment of stage IIIB non-small cell lung cancer after induction chemo-radiotherapy. |
| 22996 | A phase III double-blind, randomized, placebo-controlled study of Erythropoietin when used as an adjuvant to radiation therapy in patients with head and neck squamous cell carcinoma. EORTC 22996-24002 |
| 24971 | A randomized phase III multicenter trial of neoadjuvant docetaxel (Taxotere) plus cisplatin plus 5-fluorouracil versus neoadjuvant cisplatin plus 5-fluorouracil in patients with locally advanced inoperable squamous cell carcinoma of the head and neck |
| 08972 | Randomized phase III study comparing induction chemotherapy to daily low dose cisplatin both combined with high dose radiotherapy in patients with inoperable non-small cell lung cancer stage I, II and (low volume) stage III. |
| 22971 | A phase II feasibility study of combined accelerated external radiation and chemotherapy with 5FU and CDDP following transurethral resection in patients with muscle invasive transitional carcinoma of the bladder |
| 30971 | A feasibility study of thorough transurethral resection (TURB) and escalated dose M-VAC Chemotherapy as primary treatment of T2-T3a, N0-Nx, M0, transitional cell carcinoma of the bladder, with the intention of bladder preservation. |
| 40971 | Total Mesorectal Excision (TME) with or without pre-operative radiotherapy in the treatment of primary rectal cancer. |
| 30982 | Carboplatin in the adjuvant treatment of stage I Seminoma |
| 15961 | An international field study of the reliability and validity of the EORTC QLQ-C30 and a disease specific questionnaire module (the EORTC QLQ-OES24) in assessing quality of life of patients with oesophageal cancer (15961/40973) |
| 55954 | A randomized phase III study of chemotherapy and radiotherapy versus radiotherapy alone as adjuvant treatment to patients with node positive stages Ib or IIa cervix cancer (EO ORTC/NSGO/COSA/MRC intergroup trial) |
| 11961 | Postoperative Treatment of Glioblastoma with BNCT at the Petten Irradiation Facility |
| 22962 | A phase III study comparing conventional versus hyperfractionated radiotherapy, with or without concomitant chemotherapy, in patients with head and neck squamous cell carcinoma. |
| 26951 | Phase III study of adjuvant Procarbazine, CCNU and Vincristine chemotherapy in patients with highly anaplastic oligodendroglioma (randomized) |
| 24954 | Phase III study on larynx preservation comparing induction chemotherapy and radiotherapy versus alternating chemo-radiotherapy in resectable hypopharynx and larynx cancers (Jointly with the EORTC Radiotherapy Cooperative Group) |
| 22954 | Phase III study on larynx preservation comparing radiotherapy versus concomitant chemo-radiotherapy in resectable hypopharynx and larynx cancers (Joint study of the Radiotherapy Cooperative Group and the Head and Neck Cancer Cooperative Group). |
| 22953 | Shortened irradiation scheme, continuous 5FU and fractionation of Mitomycin C in locally advanced anal carcinoma (Joint study of the EORTC Radiotherapy Cooperative Group and the EORTC Gastrointestinal Tract Cancer Cooperative Group) |
| 08951 | Phase III trial on sequential radiotherapy with or without daily Cisplatin in patients with small cell lung cancer limited to chest and good response to induction chemotherapy |
| 30942 | A randomised Prospective Comparison of Two Schedules of Radiotherapy for Stage 1 Seminoma Testis Following Orchidectomy |
| 10932 | Phase III study of evaluation of breast irradiation in early stage, low risk breast cancer patients after complete tumor excision (Joint study of the EORTC Breast Cancer Cooperative Group and EORTC Radiotherapy Cooperative Group) |
| 08952 | Adjuvant chemotherapy in completely resected stage I, II, and IIIa non-small cell lung cancer. A prospective randomized Phase III inter-group study (In collaboration with the Adjuvant Lung Project Italy - ALPI) |
| 08941 | Randomized trial of surgery versus radiotherapy in patients with stage IIIa non-small cell lung cancer after a response to induction-chemotherapy. |
| 26882 | Phase III trial on the effect of Dibromodulcitol plus BCNU on free interval and survival of patients with supratentorial malignant brain gliomas |
| 22925 | Phase III study to evaluate a Cisplatin-Cyclophosphamide combination and an abdomino-pelvic irradiation followed by a pelvic boost in completely resected high risk stage Ia/Ib and Ic/IIa/IIb epithelial ovarian carcinomas |
| 22933 | Accelerated radiotherapy with Carbogen and Nicotinamide (ARCON) for glioblastoma. A phase I-II study |
| 22931 | Phase III randomized study on postoperative radio- and chemotherapy in patients with locally advanced head and neck carcinomas (Joint study of the EORTC Radiotherapy Cooperative Group and the Head and Neck Cancer Cooperative Group) |
| 22932 | Phase III randomized study on the role of the booster dose of postoperative radiotherapy in patients with early stage carcinomas of head and neck (Jointly with the EORTC Radiotherapy Cooperative Group) |
| 70931 | Influence of dose intensity on survival in the G-CSF supported treatment of HIV-associated non-Hodgkin's lymphomas of high malignancy: A randomized and risk-adjusted phase III multicenter trial |
| 30921 | A prospective multicenter randomized study comparing Strontium89 Chloride and palliative local field radiotherapy in patients with hormonal escaped advanced prostatic cancer |
| 08921 | UK02 EORTC/MRC/UKCCCR collaborative randomized phase III study of prophylactic cranial irradiation in patients with small cell lung cancer of limited extent who achieve a complete response to induction chemotherapy |
| 22871 | External irradiation with etanidazole radiosensitizer in advanced bladder cancer. A pilot study |
| 08891 | The role of radiotherapy in the treatment of brain metastases of small cell lung cancer. A phase II and phase III study |
| 40891 | Randomized phase III trial of radiotherapy and 5-FU treatment after curative resection for cancer of the pancreas and periampullary region |
| 24891 | Is laryngeal preservation with induction chemotherapy safe in the treatment of hypopharyngeal squamous cell carcinoma ? A randomized phase III trial |
| 08877 | Alternating versus sequential radio-chemotherapy in limited disease small cell lung cancer; a randomized phase III study |
| 55874 | Phase III study to evaluate the role of adjuvant radiotherapy in the treatment of uterine sarcomas stages I and II |
| 80871 | EORTC/MRC/SIOP/UKCCSG/CSG collaborative study to evaluate the efficacy of a chemotherapy protocol, consisting of a combination of platinum and Adriamycin in the treatment of spindle cell sarcoma of bone other than osteosarcoma. A non-randomized pilot study |
| 10873 | Phase II trial of breast conserving therapy in women with Paget's disease of the nipple |
| 40873 | Phase II clinical trial of epirubicin and cisplatin (EP) in combination with a split cause radiotherapy plus 5-Fluorouracil in locally advanced unresectable pancreatic cancer. |
| 40871 | A simple, large-scale randomized phase III trial on hepatic perfusion of 5-FU and heparin in resectable cancer of the colon and rectum |
| 22861 | Randomized phase II-III trial of radiotherapy alone or with concomitant chemotherapy in the treatment of anal carcinoma. (Jointly with the EORTC Radiotherapy Cooperative Group) |
| 24861 | Phase III Randomized Comparison of Chemotherapy with CDDP/5-FU Followed by Radiotherapy vs Radical Surgery with or without Radiotherapy in Patients with Nonmetastatic Squamous Cell Carcinoma of the Larynx |
| 08863 | CHEMOTHERAPY FOLLOWED BY SURGERY AND RADIOTHERAPY IN NSCLC PATIENTS WITH BIOPSY PROVEN N2 DISEASE. A PHASE II STUDY. |
| 08861 | Adjuvant therapy in completely resected lung cancer. A randomized phase III study in operable non-small cell lung cancer (jointly with the EORTC Radiotherapy Cooperative Group) |
| 10854 | Phase III trial of perioperative adjuvant chemotherapy in Breast Cancer |
| 22845 | Phase III trial of radiation therapy vs no radiation therapy for cerebral gliomas (low grade astrocytoma and oligodendroglioma) of the adult (Joint study of the EORTC Radiotherapy Cooperative Group, the EORTC Brain Tumor Cooperative Group and the Medical Research Council (UK)) |
| 22851 | Phase III trial of open accelerated fractionation vs conventional fractionation in the radiotherapy of advanced head and neck carcinoma |
| 26851 | Phase III trial comparing the effect of cisplatinum given during radiation therapy to radiation therapy alone in patients with supratentorial malignant brain gliomas. |
| 08845 | ADJUVANT SURGERY AFTER INDUCTION CHEMOTHERAPY IN LIMITED SMALL CELL LUNG CANCER A RANDOMIZED PROSPECTIVE STUDY. |
| 22844 | Phase III trial on low dose vs high dose radiation therapy for cerebral gliomas ( low grade astrocytoma and olidendroglioma) of the adult (Jointly with the EORTC Radiotherapy Cooperative Group) |
| 24844 | 5-FU/CDDP FOLLOWED BY SURGERY AND RADIOTHERAPY vs SURGERY AND RADIOTHERAPY IN ADVANCED SQUAMOUS CELL CARCINOMA OF LATERAL OROPHARYNX AND LATERAL POSTERIOR ORAL CAVITY (Phase III trial) |
| 22843 | Multiple fractions per day (MFD) or conventional fractionated irradiation in combination with cis-diammine dichloro platinium (II) (c-DDP) a randomized phase II study in advanced head and neck cancer. |
| 08844 | Randomized phase III trial comparing radiotherapy + weekly cisplatin vs radiotherapy + daily cisplatin for inoperable non-small cell bronchogenic carcinoma (jointly with the EORTC Radiotherapy Cooperative Group) |
| 08842 | COMBINATION CHEMOTHERAPY + SPLIT-DOSE RADIOTHERAPY, A RANDOMIZED PHASE II STUDY |
| 22831 | Phase III trial for resectable rectal cancer using postoperative pelvic radiotherapy with or without elective irradiation of para-aortic nodes and the liver |
| 40831 | Controlled clinical trial for the treatment of patients with inoperable esophageal cancer using radiotherapy and chemotherapy. |
| 22791 | Phase III trial of twice daily fractions versus single daily fraction radiotherapy in oropharyngeal carcinoma |
| 08031 | Phase II feasibility trial of induction chemotherapy followed by extrapleural pneumonectomy and postoperative radiotherapy in patients with malignant pleural mesothelioma |
| 22011 | Continuous fluorouracil plus mitomycin C versus mitomycin C plus Cisplatin as chemotherapy combination in combined radiochemotherapy for locally advanced anal cancer. A phase II-III study. |
| 22003 | A multicenter randomised trial of high versus standard doses of prophylactic cranial irradiation in limited small cell lung cancer complete responders. (An intergroup study with the PCI99-EULINT Collaborative Group, the EORTC Radiotherapy Group and the EORTC Lung Cancer Group.) |
| 20011 | A randomized trial of BEAM + PBSCT versus single agent high-dose therapy followed by BEAM + PBSCT in patients with relapsed Hodgkin's disease (HD-R2 protocol). |
| 22961 | Long term adjuvant hormonal treatment with LHRH analogue versus no further treatment in locally advanced prostatic carcinoma treated by external irradiation and a six months combined androgen blockade - A phase III study. (Joint study of the EORTC Radiotherapy Cooperative Group and the EORTC Genito-Urinary Tract Cancer Cooperative Group) |
| 22952 | No Radiotherapy versus Whole Brain Radiotherapy for 1 to 3 Brain Metastases from Solid Tumor after Surgical Resection or Radiosurgery. A Randomized Phase III Trial. |
| 40906 | Adjuvant intraoperative radiotherapy in gastric cancer. |
| 22863 | Phase III randomized clinical trial in high metastatic risk carcinoma of the prostate comparing pelvic radiotherapy plus LHRH analogue (Jointly with the EORTC Radiotherapy Cooperative Group) |
| 20982 | Prospective controlled trial in clinical stages I-II supradiaphragmatic Hodgkin'Disease. Evaluation of treatment efficacy, (long term) toxicity and Quality of Life in two different prognostic subgroups. |
| 62961 | Randomized study comparing neoadjuvant chemotherapy Etoposide + Ifosfamide + Adriamycin (EIA) combined with regional hyperthermia (RHT) Vs neoadjuvant chemotherapy alone in the treatment of high-risk soft tissue sarcomas in adults. An Intergroup study with the European Society for hyperthermic oncology. |
| 20931 | Protocol H8 for a prospective controlled trial in stage I-II supradiaphragmatic Hodgkin's disease. Evaluation of treatment efficacy and (long term) toxicity in three different prognostic subgroups. H8 Trial |
| 22921 | Four arms phase III clinical trial for T3-T4 resectable rectal cancer comparing pre-operative pelvic irradiation to pre-operative irradiation combined with fluorouracil and Leucovorin with or without post-operative adjuvant chemotherapy |
| 22911 | Phase III study of post-operative external radiotherapy in pathological stage T3N0 prostatic carcinoma (Joint study of the EORTC Radiotherapy Cooperative Group and the EORTC Genito-Urinary Tract Cancer Cooperative Group) |
| 20884 | Prospective randomized controlled trial of adjuvant involved field radiotherapy after MOPP/ABV hybrid chemotherapy in advanced Hodgkin disease. H34 Trial |
| 22881 | Phase III study in the conservative management of breast carcinoma by tumorectomy and radiotherapy: assessment of the role of a booster dose of radiotherapy (Joint study of the EORTC Radiotherapy Cooperative Group and the EORTC Breast Cancer Cooperative Group) |
| 20881 | Phase III study on Hodgkin's disease supradiaphragmatic clinical stages I and II |
| 10853 | Phase III trial of radiation therapy vs no treatment for patients with in situ ductal carcinoma of the breast (Jointly with the EORTC Radiotherapy Cooperative Group) |
| 20811 | Phase II study on morbus Hodgkin clinical stages IIIB and IV |
| 55991 | A randomized trial of adjuvant treatment with radiation plus chemotherapy versus radiation alone in high risk endometrial carcinoma. |
| 62931 | Randomized phase III trial of adjuvant chemotherapy with high-dose doxorubicin, ifosfamide and lenograstim in high grade soft tissue sarcoma. |
| 62991 | Phase II pilot study of moderate dose radiotherapy for inoperable aggressive fibromatosis |
| 22991 | Three Dimensional Conformal Radiotherapy / Intensity Modulated Radiotherapy alone vs Three Dimensional Conformal Radiotherapy / Intensity Modulated Radiotherapy plus adjuvant hormonal therapy in localized T1b-c, T2a, N0, M0 prostatic carcinoma. A Phase III Randomized Study. |
| 22922 | Phase III randomized trial investigating the role of internal mammary and medial supraclavicular (IM-MS) lymph node chain irradiation in stage I-III breast cancer (Joint study of the EORTC Radiotherapy Cooperative Group and the EORTC Breast Cancer Cooperative Group EORTC 22922/10925) |
| 22071 | Randomized Phase III trial on postoperative chemoradiation in combination with anti EGFR-antibody versus postoperative chemoradiation in head and neck squamous cell carcinomas (HNSCC) with high risk of locoregional recurrence |
| 26081 | Phase III Intergroup Study of Radiotherapy versus Temozolomide Alone versus Radiotherapy with Concomitant and Adjuvant Temozolomide for Patients with Newly Diagnosed Anaplastic Oligodendroglioma or Anaplastic Mixed Glioma with Chromosomal Co-delections of 1p and 19q. |
| 21081 | A phase III study of Ienalidomide maintenance after debulking with gemcitabine or liposomal doxorubicin +/- radiotherapy in patients with advanced cutaneous T-cell lymphoma not previously treated with intravenous chemotherapy |
| 22085 | A randomized phase III study of radiation doses and fractionation schedules for ductal carcinoma in situ (DCIS) of the breast. |
| 26082 | Radiation therapy and concurrent plus adjuvant Temsirolimus (CCI-779) versus chemo-irradiation with temozolomide in newly diagnosed glioblastoma without methylation of the MGMT gene promoter - a randomized multicenter, open-label, Phase II study. |
| 26062 | A randomized phase III study of Temozolomide and short-course radiation versus short-course radiation alone in the treatment of newly diagnosed glioblastoma multiforme in elderly patients |
| 22043 | Post-operative external radiotherapy combined with concomitant and adjuvant hormonal treatment versus post-operative external radiotherapy alone in pathological stage pT3a-b R0-1/pT2R1 N0M0, Gleason score 5-10 prostatic carcinoma. A phase III study. |
| 08072 | Concurrent once-daily versus twice-daily radiotherapy : A 2-arm randomised controlled trial of concurrent chemo-radiotherapy comparing twice-daily and once-daily radiotherapy schedules in patients with limited stage small cell lung cancer (SCLC) and good performance status (CONVERT). |
| 40054 | Preoperative chemoradiotherapy and postoperative chemotherapy with capecitabine and oxaplatin vs.capecitabine alone in locally advanced rectal cancer (PETACC-6). |
| 22042 | Adjuvant postoperative high-dose radiotherapy for atypical and malignant meningioma : a Phase II and observation study |
| 20051 | The H10 EORTC/GELA/IIL randomized Intergroup trial on early FDG-PET scan guided treatment adaptation versus standard combined modality treatment in patients with supradiaphragmatic stage I/II Hodgkin's lymphoma. |
| 22051 | Selective Use of Postoperative Radiotherapy AftEr MastectOmy (SUPREMO) |
| 55994 | Randomized phase III study of neoadjuvant chemotherapy followed by surgery vs. concomitant radiotherapy and chemotherapy in FIGO Ib2, IIa > 4 cm or IIb cervical cancer. |
| 10981 | After Mapping of the Axilla:Radiotherapy Or Surgery AMAROS |
| 22055 | Phase III study comparing post-operative conformal radiotherapy to no post-operative radiotherapy in patients with completely resected non-small cell lung cancer and mediastinal N2 involvement |
| 24061 | Randomized phase II feasibility study of Cetuximab combined with 4 cycles of TPF followed by platinum based chemo-radiation strategies |
| 24051 | Phase I/II study on induction chemotherapy followed by chemoradiation with or without lapatinib, a dual EGFR/ErbB2 kinase inhibitor, in patients with locally advanced resectable larynx and hypopharynx squamous cell. |
| 22033 | Primary chemotherapy with temozolomide vs.radiotherapy in patients with low grade gliomas after stratification for genetic 1p loss : a phase III study |
| 20991 | Diffuse large B cell and peripheral T cell non-Hodgkin's lymphomas in the elderly. Influence of prolonged oral etoposide added to CHOP combination chemotherapy in patients with good physiological status. An EORTC phase II-III trial including geriatric assessment and quality of life. |
| 20013 | Chlorambucil versus 2 X 2 Gy involved field radiotherapy in stage III/IV previously untreated follicular lymphoma patients. |
| 20992 | Diffuse large B cell and peripheral T cell NHL in the frail elderly. Progressive and cautious treatment strategy in poor status patients. A phase II trial with emphasis on geriatric assessment and quality of life. Version 2.0 (13 December 2001) |
| 20995 | Treatment of mantle cell lymphomas at advanced stages: prospective randomized comparison of myeloabative radiochemotherapy followed by blood stem cell transplantation versus maintenance with interferon alpha in first remission after initial cytoreductive chemotherapy with an anthracycline containing combination. A European Intergroup Trial. |
| 20971 | A Phase III randomized study on low-dose total body irradiation and involved field radiotherapy in patients with localized, stages I and II, low grade non-Hodgkin's lymphoma |
| 20932 | Randomized investigation of the value of radiotherapy in complete remission after chemotherapy for patients with stage II, III or IV non Hodgkin's lymphoma of intermediate or high grade histology |
| 58871 | Treatment of isolated CNS relapses occuring as first relapse in children with acute lymphoblastic leukemia by high dose Ara-C, intrathecal chemotherapy, and cranio-spinal radiotherapy. A phase II study. |
| 20871A | Phase III for the treatment of localized intermediate and high grade gastrointestinal tract non-Hodgkin's lymphoma - stage I - |
| 20871B | Phase III for the treatment of localized intermediate and high grade gastrointestinal tract non-Hodgkin's lymphoma - stage II - |
| 20856 | Maintenance of remission with recombinant alpha-2 Interferon (Roferon-A) in patients with stages III and IV low grade Non-Hodgkin's lymphoma |
| 20855 | Phase III trial comparing CHVmP/VCR-BLM vs modified ProMACE/MOPP regimen for patients with stages II, III, IV lymphomas of intermediate and high grade malignancy |
| 58832 | Phase III trial comparing as CNS prophylaxis radiotherapy vs no radiation therapy after high dose MTX for newly diagnosed acute lymphoblastic leukemia (ALL) in children with medium and high risk characteristics. |